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UK Biotech Boost The UK is launching a large-scale shift from animal testing to models created from real human cells, including mini-organs, organoids, and "organ-on-a-chip" systems. This is being done as a national program with significant funding and a clear goal: to make drug development faster, more accurate, and safer. Scientists will grow organoids from NHS patient cells - tiny structures smaller than a millimeter that replicate key functions of real organs. The goal is to address the issue that more than 90% of drugs that pass animal tests fail in human clinical trials. Mice do not get sick like humans, and their reactions often do not match human responses. Organoids solve this problem by allowing drugs to be tested directly on human tissue, specifically on the tissue of a particular patient. The project is funded by the UK Medical Research Council with £20 million. The project aims to create a library of standardized, validated organoids available to universities and pharmaceutical companies. This will enable ineffective or toxic drugs to be rejected earlier, reducing the risk to patients and decreasing the number of animals used in research. In 2025, 2.54 million animal procedures were conducted in the UK, and the government intends to accelerate the reduction of this number with new technologies. Meanwhile, Innovate UK is allocating an additional £2 million to projects that aim to reduce the use of dogs, monkeys, and other animals in safety tests, as reported in Nature Aging, July 2026. 🔗 Read original →