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Cambridge to Lead £20m Center
The University of Cambridge has announced that the £20m grant from the Medical Research Council will be used to establish a new center. This center will create and distribute human tissue models grown from patient cells from the UK's National Health Service to research groups. The center's work will utilize artificial intelligence methods. Before testing a drug on humans, developers need to understand how the substance affects the affected tissue. A model grown from a patient's cells retains some of the patient's biology and allows observation of the reaction in human cells.
One such tool is an organoid, a small, simplified tissue model grown from a patient's cells. Such models are made for the intestine, tumors, and brain. The new center will provide these models to universities and pharmaceutical companies for early candidate testing. Center director Matthias Zilbauer explains: "Since these miniature human tissues retain many unique biological features of a specific patient, they allow for more accurate study of the disease and testing of potential treatments before clinical trials."
The center aims to develop models that can be reproduced and applied in different laboratories. This way, results from patient tissues can participate in early drug candidate selection beyond a single laboratory. In November 2025, the UK government published the Replacing Animals in Science strategy and allocated £75m for it. The new center adds to this program by providing shared human tissue models for drug development.
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