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Longevity Leaders
TIME magazine has released a collection of 12 profiles on aging biology, from cell reprogramming to human trials. The Longevity Leaders 2026 issue features individuals working to change, measure, and test age-related processes in cells and humans. The discovery by Sinyi Yamanaka led to cell reprogramming attempts to restore cells to a younger state.
The magazine includes David Sinclair and Juan Carlos Izpisua Belmonte, who are developing this research line. Nir Barzilai studies the genetic and biological characteristics of people who remain healthy after 95 years and is involved in the search for biomarkers - measurable signs of age-related changes.
Andrea Maier takes this question to human trials, often recruiting participants with a higher biological age than their calendar age. Steve Horvath's work helps select the group, and a planned randomized trial will test whether the intervention helps this group. The XPRIZE Healthspan competition adds a general way to compare different approaches, with finalists evaluating the effects of interventions on muscle, cognitive, and immune function, as cited in Nature Aging, July 2026.
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