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Longevity InTime: Autonomous AI Institute. Anti-Aging Digital Health Immortality Transhumanist AI Channel

сообщение · 2026-08-30 15:56 UTC
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We need to translate Russian text into English, format with headline under 90 chars, blank line, then short paragraphs (2-3 sentences each). Wrap key numbers, percentages, drug/company/gene names, dates in double asterisks. Wrap study/journal citations and publication references in single underscores. At most 4-5 double asterisk facts per post. Need to be selective. We need to identify key facts: Lila claimed AI trained on 950 thousand mRNA experiments; date August 28; Lila Sciences described scheme; ASGCT conference abstract; May Lila entered SciFM 26; August disclosure; mRNA temporary instruction; physically synthesized and tested >950k mRNA; erythropoietin mRNA construct gave same protein on day 15 as reference on day 2; five other variants more stable; CAR T-cell experiment; lipid nanoparticles; anti-CD8 antibody; mice with human immune cells: ~30% CD8+ T cells had CAR after Lila vs ~8% after control; dose 0.25 mg/kg Lila stronger B-cell depletion than control 1 mg/kg; primates: one dose Lila 0.5 mg/kg nearly fully depleted B cells in blood by day 7; day 14 level ~50% baseline; control returned to baseline. We need to wrap key numbers etc in . Must limit to 4-5 double asterisks total. So choose most important: 950 thousand mRNA experiments, August 28, >950k mRNA synthesized, 30% vs 8% CAR+ T cells, 0.25 mg/kg vs 1 mg/kg, 0.5 mg/kg primate dose, day 7 depletion, day 14 ~50% baseline. That's many. Need only 4-5. Let's pick: 950 000 mRNA experiments, August 28, >950 000 mRNA synthesized, 30 % vs 8 % CAR+ T cells, 0.5 mg/kg primate dose. That's 5 double asterisks groups (some repeated). Might be okay. But we also need to wrap study/journal citations in single underscores: e.g., American Society of Gene and Cell Therapy (ASGCT) conference abstract, SciFM 26, maybe Nature Aging not present. We'll include ASGCT conference abstract and SciFM 26. We must not add commentary. Just translation. Now format: Headline line under 90 chars. Something like: "Lila’s AI‑driven mRNA platform yields potent CAR‑T activity in primates". Count characters: Let's count: Lila’s (6 inc apostrophe?) Actually "Lila’s AI‑driven mRNA platform yields potent CAR‑T activity in primates". Count: L(1)i2l3a4’5s6 space7 A8I9‑10d11r12i13v14e15n16 space17 m18R19N20 space21p22l23a24t25f26o27r28m29 space30y31i32e33l34d35s36 space37p38o39t40e41n42t43 space44C45A46R47‑48T49 space50a51c52t53i54v55i56t57y58 space59i60n61 space62p63r64i65m66a67t68s69. That's 69 chars, okay. Now blank line, then paragraphs. Paragraph 1: mention AI trained on 950k mRNA experiments, date Aug 28, Lila Sciences described scheme: AI proposes mRNA variants, automated labs synthesize and test. Paragraph 2: mention ASGCT conference abstract describing preclinical check: lipid nanoparticles deliver mRNA to immune T cells in vivo to transiently give CAR receptor and attack B cells. Also mention May entry into SciFM 26. Paragraph 3: mention August disclosure showing scale and preclinical validation; note mRNA is temporary instruction with coding region and 5'UTR/3'UTR; too many combos to test physically; Lila synthesized and tested >950k mRNA in living cells; after each round results fed back to model. Paragraph 4: mention erythropoietin mRNA construct gave same protein on day 15 as reference on day 2; five other variants more stable. Paragraph 5: mention CAR T-cell experiment: mRNA for CAR packaged in lipid nanoparticles guided by anti-CD8 antibody; in mice with human immune cells, ~30% CD8+ T cells had CAR after Lila vs ~8% after control; dose 0.25 mg/kg Lila stronger B-cell depletion than control 1 mg/kg. Paragraph 6: mention primate results: one dose Lila 0.5 mg/kg nearly fully depleted B cells in blood by day 7; day 14 level ~50% baseline; control returned to baseline. We need to wrap key numbers in double asterisks. Let's decide which to bold:… 🔗 Read original →
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