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We need to translate Russian news post into natural English, format per rules.
First line: short headline under 90 chars. No markdown, no '#'.
Then blank line, then body split into short paragraphs (2-3 sentences each), separated by blank lines.
Wrap few genuinely important facts — key numbers, percentages, drug/company/gene names, dates — in double asterisks. At most 4-5 per post.
Wrap study/journal citations and publication references in single underscores (e.g. Nature Aging, July 2026).
We need to preserve facts, numbers, names, citations exactly. No added commentary.
We need to identify key facts: date 31 августа (August 31) in Nature Communications described FATE. Gene LMNA, progerin, farnesyl, etc. Numbers: 322 of 323 progerin-positive muscle cells lacked γH2AX foci; 53BP1 retained at nuclear envelope. Also editing efficiency max 8.55% after ten days. Also maybe mention Hutchinson-Gilford progeria syndrome (HGPS). Also mention that FATE replaces one letter in LMNA tail. Also mention lipid nanoparticles delivering mRNA.
We need to select at most 4-5 double-asterisk facts. Choose: date (August 31), journal Nature Communications, gene LMNA, progerin, farnesyl, numbers 322/323, editing efficiency 8.55%, maybe Hutchinson-Gilford progeria syndrome. But we need to be selective: at most 4-5. Let's pick: August 31, Nature Communications, LMNA, progerin, farnesyl, 322 of 323, 8.55%. That's many. Need max 4-5. Let's choose: August 31, Nature Communications, LMNA, progerin, 8.55% maybe also 322 of 323. That's 6. Need reduce.
We can combine some: maybe we can put date and journal together? But each double asterisk wraps a fact; we could put "August 31 in Nature Communications" but the citation should be underscores, not double asterisks. So date could be double asterisk, journal underscores. So date August 31 is one. Journal Nature Communications is underscores (not counted). Then we need gene name LMNA maybe double asterisk? Could be considered important. Progerin maybe double asterisk? Farnesyl maybe double asterisk? Number 322 of 323 maybe double asterisk. Editing efficiency 8.55% maybe double asterisk. That's many.
We need at most 4-5 double asterisk facts. Let's decide which are most important: date, journal (underscores), LMNA gene, progerin, farnesyl, editing efficiency, 322/323. Perhaps we can combine LMNA and progerin into one fact? Not really.
We could choose: LMNA, progerin, farnesyl, 8.55%, 322 of 323. That's 5. Date and journal can be in underscores? Date cannot be underscores because it's not a citation. But we could put date in double asterisk as well, but then exceed limit. Maybe we can omit date double asterisk and just mention date in plain text? The rule: wrap the few genuinely important facts — key numbers, percentages, drug/company/gene names, dates — in double asterisks. So dates should be double asterisk if we consider them important. But we can maybe not treat date as key fact? It's somewhat important but maybe we can skip double asterisk for date and just mention normally. The rule says wrap the few genuinely important facts — key numbers, percentages, drug/company/gene names, dates — in double asterisks. It implies we should wrap those categories, but we can be selective: at most 4-5 per post. So we need to choose which dates, numbers, etc to wrap. We can omit date wrapping if we stay within limit.
Thus we can wrap: LMNA, progerin, farnesyl, 8.55%, 322 of 323. That's 5.
Now we need to wrap study/journal citations in single underscores: Nature Communications. Also maybe mention Hutchinson-Gilford progeria syndrome (HGPS) but not wrap.…
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