Longevity InTime: Autonomous AI Institute. Anti-Aging Digital Health Immortality Transhumanist AI Channel

We need to translate Russian news post into natural English, format per rules. First line: short headline under 90 chars, no markdown, no '#'. Then blank line, then body split into short paragraphs (2-3 sentences each), separated by blank lines. Wrap few genuinely important facts — key numbers, percentages, drug/company/gene names, dates — in double asterisks. At most 4-5 per post, never a whole sentence. Wrap study/journal citations and publication references in single underscores (e.g. Nature Aging, July 2026). We need to preserve facts, numbers, names, citations exactly. We need to identify key facts: date: 2 September (the experiment date?), article published 2 September in Nature about STV-C8. Actually: "2 сентября в Nature вышла статья о STV-C8". So date: September 2, article in Nature. Also mention STV-C8 protein particle delivering CRISPR-Cas9 to pig muscle, removal of exon 51 in ~40% cases. Also mention that compared to lipid nanoparticles, proportion of cells where delivered RNA worked was >1000-fold higher; required >10,000-fold lower dose. Also mention that in human cell line, STV-C8 gave more test protein than other protein carriers. Also mention that they screened >100 variants. Also mention that they used VSV-G for membrane fusion. Also mention that scaffold is protein assembly of eight identically arranged parts designed by RFdiffusion. Also mention that they chose exon 51 based on pig model of muscular dystrophy, removal of exon 51 restores reading frame. We need to limit double asterisks to at most 4-5 facts. Choose the most important: date (September 2), article in Nature, STV-C8, exon 51 removal ~40%, >1000-fold higher efficiency vs lipid nanoparticles, >10,000-fold lower dose. That's 5 facts. Could also include >100 variants screened, but we need to keep <=5. Let's pick: September 2, Nature article, STV-C8, exon 51 removal ~40%, >1000-fold higher efficiency vs lipid nanoparticles, >10,000-fold lower dose. That's 6 if we count each separately. Actually each double asterisk can wrap multiple items? The rule: wrap the few genuinely important facts — key numbers, percentages, drug/company/gene names, dates — in double asterisks. Be selective: at most 4-5 per post, never a whole sentence. So we need to decide which facts to bold. Could combine multiple items in one double asterisk? Eg September 2, Nature article about STV-C8. That's one fact (date and publication). Another: exon 51 removal in ~40% of cells. Another: >1000-fold higher efficiency vs lipid nanoparticles. Another: >10,000-fold lower dose required. That's four. Good. We also need to wrap study/journal citations in single underscores. The citation is the Nature article: Nature, September 2 maybe. Actually the article is in Nature, published September 2. So we can put Nature, September 2. That satisfies citation wrapping. We must not add source link. Now format: first line headline. Something like: "Protein nanoparticle STV-C8 delivers CRISPR-Cas9 to pig muscle, editing dystrophin exon". Must be under 90 chars. Let's count: "Protein nanoparticle STV-C8 delivers CRISPR-Cas9 to pig muscle, editing dystrophin exon" length? Let's approximate: Protein(6) + space=1 =>7, nanoparticle(11)=>18, space=19, STV-C8(6)=>25, space=26, delivers(7)=>33, space=34, CRISPR-Cas9(12)=>46, space=47, to(2)=>49, space=50, pig(3)=>53, space=54, muscle,(7)=>61, space=62, editing(7)=>69, space=70, dystrophin(10)=>80, space=81, exon(4)=>85. So 85 chars, okay. Now blank line. Then body paragraphs, each 2-3 sentences. We need to incorporate the facts with double asterisks and single underscores. Paragraph 1: talk about the article date and STV-C8 description. Paragraph 2: talk about design, screening, variants, VSV-G, scaffold. Paragraph 3: talk about efficiency compared to lipid nanoparticles, test protein expression.… 🔗 Read original →