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First single out one framework to learn, preferably one you have interest in. For example, if you're into gaming, choose Pygame. For AI (or LLM) -programming > PyTorch, websites > Django, APIs (used to connect different programs, i.e. to plug in external services into your existing program) > FastAPI. There are many more Python frameworks, and without knowing which to learn, it's challenging to move on to the how.