Qt for Python (PySide/Shiboken)

Hello! I'm releatively new to the Qt for Python (previously work with PyQt with classical Qt widgets). My question is, can I write my GUI in QML and embed it into the Python app? Important part is that I want to all elements to look as much natively as possible on every OS (Win, UNIX, Mac) as it was when I've used the QtWidgets approach. Ideally, the QML should handle all the GUI-related stuff and Python should only respond on user actions via the bound actions callbacks. Can you point me on the most useful information about this topic? Thanks!