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I'm relatively sure that doing only @Property(bool, notify=Signal(name="runFilterChanged")) will cause the Signal() instance (the PyObject wrapping the underlying C++ object) to get GC'ed, but I'm not 100% on that. If you pass something to a Qt function, it will not keep a reference to the PyObject, but only the wrapped object. If there's no reference to the wrapper in Python code, the GC will eat it.